Geometric Analysis of the Human Spine for image-based diagnosis, biomechanical analysis, and neurosurgery
Within Spine-Analysis project, articulated shape models of the human spine for surgeon planning are developed. In cooperation with the Medical Center of the Johannes...
Design of Experiments (DoE) is a field at the interface between mathematical optimization and statistics, which aims at optimally selecting experimental conditions before...
The main objective of this project is to develop an adaptive sampling strategy for the identification of cycles in transition networks. To analyse transition networks...
Lossy compression for more efficient communication in high performance computing
While the compute power of HPC systems increases substantially, the bandwidth and latency for communication is not improved at the same rate. In this project, we address...
The project develops an adaptive mesh refinement method based on
a continuous PDE relaxation that can be used as a plug-in in branch&bound
solvers as the CIP optimizer...
Analysis tools for dynamic interfaces to understand nanostrutures
Bioinspired mussel adhesives that bound to the nanometer-sized metal oxide particles exhibit phenomenal nanomaterial properties. Those material specific binding domains...
BRAIN, the Berlin Research Area Information Network, is the high speed data net of Berlin’s public institutions for science, education and culture.
It came into being on...
Treating Osteoarthritis in Knee with Mimicked Interpositional Spacer
One aim of this project is to analyze a large set of medical image data with respect to the anatomy of the knee joint. The aim is to determine the variation in shape of...
While a relationship between knee joint laxity and osteoarthritis is often assumed, the exact mechanism is not yet fully understood. It is not clear how stabilization by...
Analysis and quantification of morphological and structural changes in cartilage
Within the PrevOP research network "Preventing the progression of primary Osteoarthritis by high impact long-term Physical exercise regimen – key mechanisms, efficacy...
Machine Learning Approaches for Enhanced, Shape Model Based 3D Image Segmentation
Fully automatic segmentation of arbitrary anatomical structures from 3D medical image data is a challenging, yet unsolved problem. Though fully automatic segmentation is...
Photoacoustic (PA) imaging uses short optical pulses that are absorbed in tissue and cause ultrasound waves. The ultrasound waves are recorded, and reconstruction...
In biological research, microscopy is a powerful tool to investigate morphological changes in tissues and cell cultures. Modern setups are able to produce 100000 and more...
To investigate the migration behavior of cells, we have developed a method that tracks single cells in phase-contrast microscopy. In contrast to staining-based approaches...
This project aims to advance optical materials for photovoltaics and photonics, with textures on nanometer scales. To do this, we perform rigorous 3D simulations for...
Crystallization: interactions of Drug molecules with small organic solvents
Introduction
Polymorphism in drug molecules is an important property, since it can govern the solubility, release profile and thus the overall efficacy of the formulation...
Active Thermography for Fiber-Reinforced Composites
Carbon-fiber reinforced composites are becoming more and more important in the production of light-weight structures, e.g. in the automotive industry. Thermography is...
The project is part of the so called 'Basisprojekt' Attention & Form within the DFG Cluster of Excellence 'Bild Wissen Gestaltung'. The aim of the project is to analyze...
Changes in cells while they are undergoing transformation from "normal" to malignant cells (e.g. during infections) happen on many biological levels, such as genome...
Osteoarthritis of the knee (OAK) is a complex multi-factor disease resulting from mechanical abnormalities involving degradation of joints including articular cartilage...
